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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Forthcoming changes
    Planned changes for UniProt

  • UniProt release 2016_09
    Ki-67: the great leap from simple marker to functional actor | Change of RDF representation of the cross-references to family and domain...

  • UniProt release 2016_08
    Butterfly fashion: all they need is cortex | Cross-references to CDD | Change of the cross-references to VectorBase and WormBase | Pepti...

  • UniProt release 2016_07
    (Bacterial) immigration under control

  • UniProt release 2016_06
    Strength through unity | Removal of the cross-references to NextBio | Change of URIs for neXtProt

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Retrieve/ID mapping
    This tool merges the "Retrieve" and "ID Mapping" tools

  • Peptide search
    Find sequences that exactly match a query peptide sequence

UniProt data

Protein spotlight

you want it darker

We are highly adaptable. We have been for the past few million years, and continue to be so on a daily basis. Whichever way you look at it, the art of adaptation really is just a way of preserving your integrity - physical or psychological - and coping the best way possible with the environment you are evolving in…