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Keyword - Activation of host caspases by virus (KW-1073)

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Viral protein involved in the activation of host cell apoptosis by acting on host caspases. While many viruses encode protein that inhibit apoptosis, viruses can also use apoptosis to their advantage to suppress immune response or to disseminate. Therefore, some viral proteins are able to cleave or activate caspases in order to promote apoptosis.


Biological process


induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [ GO:0039651 ]


Activation of host caspases by virusHost-virus interactionModulation of host cell apoptosis by virusBiological process