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P85048 (PAG75_BUBBU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pregnancy-associated glycoprotein 75

Short name=PAG 75
EC=3.4.23.-
Alternative name(s):
Pregnancy-associated glycoprotein 60K
Pregnancy-associated glycoprotein 63H
Pregnancy-associated glycoprotein 69A
Pregnancy-associated glycoprotein 76D
Pregnancy-associated glycoprotein 76G
OrganismBubalus bubalis (Domestic water buffalo)
Taxonomic identifier89462 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBubalus

Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted Ref.1.

Tissue specificity

Expressed in chorionic epithelium (trophectoderm). Ref.1 Ref.2

Developmental stage

Expressed during month 5 of pregnancy. Ref.1 Ref.2

Post-translational modification

N-glycosylated By similarity. UniProtKB P84917

Sequence similarities

Belongs to the peptidase A1 family.

Ontologies

Keywords
   Cellular componentSecreted
   Molecular functionAspartyl protease
Hydrolase
Protease
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaspartic-type endopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›20›20Pregnancy-associated glycoprotein 75
PRO_0000271230

Experimental info

Non-terminal residue201

Sequences

Sequence LengthMass (Da)Tools
P85048 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 364AEA440F18D95A

FASTA202,373
        10         20 
RGSXLTIHPL RNIRDFFYVG 

« Hide

References

[1]"Isolation of new pregnancy-associated glycoproteins from water buffalo (Bubalus bubalis) placenta by Vicia villosa affinity chromatography."
Barbato O., Sousa N.M., Klisch K., Clerget E., Debenedetti A., Barile V.L., Malfatti A., Beckers J.F.
Res. Vet. Sci. 85:457-466(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
Tissue: Trophectoderm.
[2]"Purification of pregnancy-associated glycoproteins from late-pregnancy Bubalus bubalis placentas and development of a radioimmunoassay for pregnancy diagnosis in water buffalo females."
Barbato O., Melo de Sousa N., Barile V.L., Canali C., Beckers J.F.
BMC Vet. Res. 9:89-89(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-10, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
Tissue: Fetal cotyledon.

Cross-references

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry namePAG75_BUBBU
AccessionPrimary (citable) accession number: P85048
Secondary accession number(s): P86369 expand/collapse secondary AC list , P86372, P86375, P86378, P86379
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: April 16, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries