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Protein

Pregnancy-associated glycoprotein 75

Gene
N/A
Organism
Bubalus bubalis (Domestic water buffalo)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. aspartic-type endopeptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Aspartyl protease, Hydrolase, Protease

Names & Taxonomyi

Protein namesi
Recommended name:
Pregnancy-associated glycoprotein 75 (EC:3.4.23.-)
Short name:
PAG 75
Alternative name(s):
Pregnancy-associated glycoprotein 60K
Pregnancy-associated glycoprotein 63H
Pregnancy-associated glycoprotein 69A
Pregnancy-associated glycoprotein 76D
Pregnancy-associated glycoprotein 76G
OrganismiBubalus bubalis (Domestic water buffalo)
Taxonomic identifieri89462 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBubalus

Subcellular locationi

Secreted 1 Publication

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›20›20Pregnancy-associated glycoprotein 75PRO_0000271230Add
BLAST

Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Expressioni

Tissue specificityi

Expressed in chorionic epithelium (trophectoderm).2 Publications

Developmental stagei

Expressed during month 5 of pregnancy.2 Publications

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase A1 family.Sequence Analysis

Sequencei

Sequence statusi: Fragment.

P85048-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20
RGSXLTIHPL RNIRDFFYVG
Length:20
Mass (Da):2,373
Last modified:January 9, 2007 - v1
Checksum:i364AEA440F18D95A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei20 – 201

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Isolation of new pregnancy-associated glycoproteins from water buffalo (Bubalus bubalis) placenta by Vicia villosa affinity chromatography."
    Barbato O., Sousa N.M., Klisch K., Clerget E., Debenedetti A., Barile V.L., Malfatti A., Beckers J.F.
    Res. Vet. Sci. 85:457-466(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Tissue: Trophectoderm.
  2. "Purification of pregnancy-associated glycoproteins from late-pregnancy Bubalus bubalis placentas and development of a radioimmunoassay for pregnancy diagnosis in water buffalo females."
    Barbato O., Melo de Sousa N., Barile V.L., Canali C., Beckers J.F.
    BMC Vet. Res. 9:89-89(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-10, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    Tissue: Fetal cotyledon.

Entry informationi

Entry nameiPAG75_BUBBU
AccessioniPrimary (citable) accession number: P85048
Secondary accession number(s): P86369
, P86372, P86375, P86378, P86379
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 7, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.