P85049 (PAG70_BUBBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Pregnancy-associated glycoprotein 70 Short name=PAG 70 EC=3.4.23.-
Organism	Bubalus bubalis (Domestic water buffalo)
Taxonomic identifier	89462 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bubalus

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Ref.1.
Tissue specificity	Expressed in chorionic epithelium (trophectoderm). Ref.1
Developmental stage	Expressed during month 5 of pregnancy. Ref.1
Post-translational modification	N-glycosylated By similarity. UniProtKB P84916
Sequence similarities	Belongs to the peptidase A1 family.

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Aspartyl protease Hydrolase Protease
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	Pregnancy-associated glycoprotein 70		PRO_0000271229
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	P85049 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 5CCD0A672A8FEBFD	FASTA	15	1,692
	10 RGSXLTILPL RNIID

References

[1]

"Isolation of new pregnancy-associated glycoproteins from water buffalo (Bubalus bubalis) placenta by Vicia villosa affinity chromatography." Barbato O., Sousa N.M., Klisch K., Clerget E., Debenedetti A., Barile V.L., Malfatti A., Beckers J.F. Res. Vet. Sci. 85:457-466(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Tissue: Trophectoderm.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00141. ASP_PROTEASE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PAG70_BUBBU

Accession

Primary (citable) accession number: P85049

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	November 16, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program