P86372 (PA69A_BUBBU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Pregnancy-associated glycoprotein 69A EC=3.4.23.-
Organism	Bubalus bubalis (Domestic water buffalo)
Taxonomic identifier	89462 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bubalus

Protein attributes

Sequence length	9 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted › extracellular space By similarity UniProtKB P85322.
Tissue specificity	Expressed in chorionic epithelium (trophectoderm). Ref.1
Developmental stage	Expressed during 8th month of pregnancy. Ref.1
Post-translational modification	N-glycosylated By similarity. UniProtKB P85322
Sequence similarities	Belongs to the peptidase A1 family.

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Aspartyl protease Hydrolase Protease
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	extracellular space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›9	›9	Pregnancy-associated glycoprotein 69A		PRO_0000389540
Experimental info
	Non-terminal residue	9	1

Sequences

	Sequence		Length	Mass (Da)
	P86372 [UniParc]. Last modified November 24, 2009. Version 1. Checksum: 2BFBE041A73AF5B8	FASTA	9	991
	RGSXLTIHP

References

[1]

"Purification and development of radioimmunoassay for pregnancy-associated glycoproteins isolated in water buffalo (Bubalus bubalis)." Barbato O., Sousa N.M., Barile V.L., Canali C., Beckers J.F. Anim. Reprod. Sci. 0:0-0(2009) Cited for: PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Tissue: Trophectoderm.

Cross-references

3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00141. ASP_PROTEASE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PA69A_BUBBU

Accession

Primary (citable) accession number: P86372

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 24, 2009
Last sequence update:	November 24, 2009
Last modified:	November 16, 2011
This is version 3 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program