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Protein

Protein L2

Gene

L2R

Organism
Vaccinia virus (strain Copenhagen) (VACV)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Early protein involved in early virion morphogenesis. Participates in the formation and elongation of crescent-shaped membrane precursors of immature virions in cytoplasmic factories (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein L2
Gene namesi
ORF Names:L2R
OrganismiVaccinia virus (strain Copenhagen) (VACV)
Taxonomic identifieri10249 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000008269 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei67 – 87HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Membrane, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000996171 – 87Protein L2Add BLAST87

Proteomic databases

PRIDEiP20843

Expressioni

Inductioni

Expressed in the early phase of the viral replicative cycle.

Keywords - Developmental stagei

Early protein

Structurei

3D structure databases

SMRiP20843
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chordopoxvirinae L2 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG0900023P

Family and domain databases

InterProiView protein in InterPro
IPR008447 Prot_L2
PfamiView protein in Pfam
PF05803 Chordopox_L2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD019912 Chordopox_L2, 1 hit

Sequencei

Sequence statusi: Complete.

P20843-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVIADRLDD IVKQNIADEK FVDFVIHGLE HQCPAILRPL IRLFIDILLF
60 70 80
VIVIYIFTVR LVSRNYQMLL ALVALVITLT IFYYFIL
Length:87
Mass (Da):10,225
Last modified:February 1, 1991 - v1
Checksum:iC3BA27F8E59C448E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA Translation: AAA48077.1
PIRiI42512

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M35027 Genomic DNA Translation: AAA48077.1
PIRiI42512

3D structure databases

SMRiP20843
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP20843

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG0900023P

Family and domain databases

InterProiView protein in InterPro
IPR008447 Prot_L2
PfamiView protein in Pfam
PF05803 Chordopox_L2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD019912 Chordopox_L2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiL2_VACCC
AccessioniPrimary (citable) accession number: P20843
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: May 23, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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