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Protein
Submitted name:

Carbonic anhydrase, GAG-binding IMV membrane protein

Gene

E8L

Organism
Monkeypox virus
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Carbonic anhydrase, GAG-binding IMV membrane proteinImported
Submitted name:
E8LImported
Gene namesi
Name:E8LImported
ORF Names:MPXV-CAM1990_02-097Imported, MPXV-Congo_8-098Imported, MPXV-GAB1988_001-098Imported, MPXV-Ikubi-097Imported, MPXV_DRC_Yandongi_106Imported, MPXV_SUD2005_01_106Imported, MPXV_ZAI1979_005_110Imported, MPXVgp105Imported
OrganismiMonkeypox virusImported
Taxonomic identifieri10244 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirus
Virus hostiCynomys gunnisoni (Gunnison's prairie dog) [TaxID: 45479]
Cynomys leucurus (White-tailed prairie dog) [TaxID: 99825]
Cynomys ludovicianus (Black-tailed prairie dog) [TaxID: 45480]
Cynomys mexicanus (Mexican prairie dog) [TaxID: 99826]
Cynomys parvidens (Utah prairie dog) [TaxID: 99827]
Gliridae (dormice) [TaxID: 30650]
Heliosciurus ruwenzorii (Ruwenzori sun squirrel) [TaxID: 226685]
Homo sapiens (Human) [TaxID: 9606]
Mus musculus (Mouse) [TaxID: 10090]
Proteomesi

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei276 – 294HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

SMRiQ3I8Q9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 235Alpha-carbonic anhydraseInterPro annotationAdd BLAST235

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q3I8Q9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPQQLSPINI ETKKAISDTR LKTLDIHYNE SKPTTIQNTG KLVRINFKGG
60 70 80 90 100
YISGGFLPNE YVLSTIHIYW GKEDDYGSNH LIDVYKYSGE INLVHWNKKK
110 120 130 140 150
YSSYEEAKKH DDGIIIIAIF LQVSDHKNVY FQKIVNQLDS IRSANMSAPF
160 170 180 190 200
DSVFYLDNLL PSTLDYFTYL GTTINHSADA AWIIFPTPIN IHSDQLSKFR
210 220 230 240 250
TLLSSSNHEG KPHYITENYR NPYKLNDDTQ VYYSGEIIRA ATTSPVRENY
260 270 280 290 300
FMKWLSDLRE ACFSYYQKYI EGNKTFAIIA IVFVFILTAI LFLMSQRYSR

EKQN
Length:304
Mass (Da):35,278
Last modified:November 8, 2005 - v1
Checksum:i8A3E0886BDA8FBFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ011155 Genomic DNA Translation: AAY97305.1
HQ857562 Genomic DNA Translation: ADX22752.1
KC257459 Genomic DNA Translation: AGF36661.1
KC257460 Genomic DNA Translation: AGF36868.1
JX878408 Genomic DNA Translation: AGR34656.1
JX878409 Genomic DNA Translation: AGR34847.1
JX878410 Genomic DNA Translation: AGR35038.1
JX878411 Genomic DNA Translation: AGR35229.1
JX878412 Genomic DNA Translation: AGR35420.1
JX878413 Genomic DNA Translation: AGR35611.1
JX878414 Genomic DNA Translation: AGR35802.1
JX878415 Genomic DNA Translation: AGR35993.1
JX878416 Genomic DNA Translation: AGR36184.1
JX878417 Genomic DNA Translation: AGR36375.1
JX878418 Genomic DNA Translation: AGR36566.1
JX878419 Genomic DNA Translation: AGR36757.1
JX878420 Genomic DNA Translation: AGR36948.1
JX878421 Genomic DNA Translation: AGR37139.1
JX878422 Genomic DNA Translation: AGR37330.1
JX878426 Genomic DNA Translation: AGR38091.1
JX878427 Genomic DNA Translation: AGR38282.1
JX878428 Genomic DNA Translation: AGR38473.1
KJ642612 Genomic DNA Translation: AIE40190.1
KJ642613 Genomic DNA Translation: AIE40368.1
KJ642618 Genomic DNA Translation: AIE41247.1
KJ642619 Genomic DNA Translation: AIE41425.1
KP849471 Genomic DNA Translation: AKG51453.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ011155 Genomic DNA Translation: AAY97305.1
HQ857562 Genomic DNA Translation: ADX22752.1
KC257459 Genomic DNA Translation: AGF36661.1
KC257460 Genomic DNA Translation: AGF36868.1
JX878408 Genomic DNA Translation: AGR34656.1
JX878409 Genomic DNA Translation: AGR34847.1
JX878410 Genomic DNA Translation: AGR35038.1
JX878411 Genomic DNA Translation: AGR35229.1
JX878412 Genomic DNA Translation: AGR35420.1
JX878413 Genomic DNA Translation: AGR35611.1
JX878414 Genomic DNA Translation: AGR35802.1
JX878415 Genomic DNA Translation: AGR35993.1
JX878416 Genomic DNA Translation: AGR36184.1
JX878417 Genomic DNA Translation: AGR36375.1
JX878418 Genomic DNA Translation: AGR36566.1
JX878419 Genomic DNA Translation: AGR36757.1
JX878420 Genomic DNA Translation: AGR36948.1
JX878421 Genomic DNA Translation: AGR37139.1
JX878422 Genomic DNA Translation: AGR37330.1
JX878426 Genomic DNA Translation: AGR38091.1
JX878427 Genomic DNA Translation: AGR38282.1
JX878428 Genomic DNA Translation: AGR38473.1
KJ642612 Genomic DNA Translation: AIE40190.1
KJ642613 Genomic DNA Translation: AIE40368.1
KJ642618 Genomic DNA Translation: AIE41247.1
KJ642619 Genomic DNA Translation: AIE41425.1
KP849471 Genomic DNA Translation: AKG51453.1

3D structure databases

SMRiQ3I8Q9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ3I8Q9_MONPV
AccessioniPrimary (citable) accession number: Q3I8Q9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: July 18, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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